Introduction
One of the most common sources of confusion when using semaglutide is converting units from an insulin syringe into milligrams (mg) of medication. If you’ve been prescribed 30 units of semaglutide, you may be wondering exactly how much that equals in milligrams. The answer depends on the concentration (mg per mL) of your semaglutide vial, since compounding pharmacies can prepare it in different strengths.
Units, Milliliters, and Syringe Measurements
When using a standard U-100 insulin syringe, the markings are based on insulin units:
- 100 units = 1 mL
- 30 units = 0.3 mL
So, when you draw up 30 units, you’re really drawing up 0.3 mL of semaglutide. But to find out how many milligrams (mg) this equals, you need to know the vial’s concentration.
Common Concentrations of Semaglutide
Compounded semaglutide often comes in one of these strengths:
- 2.5 mg/mL
- 5 mg/mL
Converting 30 Units to mg
- At 2.5 mg/mL:
30 units (0.3 mL) = 0.75 mg of semaglutide - At 5 mg/mL:
30 units (0.3 mL) = 1.5 mg of semaglutide
This shows why it’s essential to always check your prescription label. The same 30 units can equal different doses depending on your vial.
Why the Concentration Matters
Because semaglutide dosing is typically very precise and increases gradually over time, even a small miscalculation can make a big difference. Taking too much may worsen side effects like nausea or vomiting, while taking too little could slow down your weight loss or blood sugar control progress. Always verify the concentration with your pharmacy before drawing up your dose.

FAQs
How many mg is 30 units of semaglutide?
- At 2.5 mg/mL, 30 units = 0.75 mg
- At 5 mg/mL, 30 units = 1.5 mg
What does 30 units mean on an insulin syringe?
On a U-100 syringe, 30 units = 0.3 mL of liquid.
Why do pharmacies use different concentrations?
Compounded semaglutide can be prepared differently depending on the pharmacy. This is why always checking the label is critical.
How can I calculate my own dose?
Use this formula:
mg = (mL drawn up) × (mg per mL concentration)
Final Thoughts
If you’re measuring 30 units of semaglutide, that equals 0.3 mL of medication. The actual milligram amount depends on your vial’s strength: 0.75 mg at 2.5 mg/mL or 1.5 mg at 5 mg/mL. Always check the concentration printed on your vial and confirm with your healthcare provider to ensure you’re taking the correct dose.